{"id":93023,"date":"2021-11-27T23:46:37","date_gmt":"2021-11-27T22:46:37","guid":{"rendered":"https:\/\/radioljubuski.ba\/?p=93023"},"modified":"2021-11-27T23:46:38","modified_gmt":"2021-11-27T22:46:38","slug":"imunolog-trobonjaca-je-zabrinut-ako-novi-soj-virusa-iz-afrike-bude-imao-snazniji-prodor-postojeca-cjepiva-zasigurno-nece-biti-ucinkovita","status":"publish","type":"post","link":"https:\/\/radioljubuski.ba\/index.php\/2021\/11\/27\/imunolog-trobonjaca-je-zabrinut-ako-novi-soj-virusa-iz-afrike-bude-imao-snazniji-prodor-postojeca-cjepiva-zasigurno-nece-biti-ucinkovita\/","title":{"rendered":"Imunolog Trobonja\u010da je zabrinut: Ako novi soj virusa iz Afrike bude imao sna\u017eniji prodor, postoje\u0107a cjepiva zasigurno ne\u0107e biti u\u010dinkovita"},"content":{"rendered":"\n

Znanstvenici u Ju\u017enoafri\u010dkoj Republici objavili su u \u010detvrtak da su identificirali novu varijantu COVID-a 19 s vi\u0161estrukim mutacijama, koju smatraju odgovornom za velik porast broja zara\u017eenih, a ve\u0107 dan kasnije na\u0161 Nacionalni sto\u017eer civilne za\u0161tite donio je mjere ograni\u010denja na granicama za putnike iz nekoliko zemalja.<\/p>\n\n\n\n

Odluka o prelasku granice odnosi se na dolaske iz Bocvane, Lesota, Namibije, Zimbabvea i Konga te zna\u010di zabranu ulaska za strance, a za hrvatske dr\u017eavljane uvo\u0111enje 14-dnevne karantene i obveznog testiranja.<\/p>\n\n\n\n

Me\u0111utim, istog dana stigla je vijest da je novi soj prona\u0111en u Izraelu i Belgiji, \u0161to zvu\u010di jako lo\u0161e iz nekoliko razloga. Znanstvenici se zbog svega onoga \u0161to se do sada zna o novom soju pribojavaju crnog scenarija, odnosno povratka krize s epidemijom na po\u010detak, s obzirom na to da bi na toliki broj mutacija koji je uo\u010den na razini \u0161iljka spike proteina kod ovog soja, cjepiva vjerojatno bila neu\u010dinkovita.<\/p>\n\n\n\n

Potvrdio nam je to na\u0161 poznati imunolog dr. Zlatko Trobonja\u010da,<\/strong> kojeg smo zatekli prili\u010dno zabrinutog.<\/p>\n\n\n\n

– Svakako pozdravljam ove mjere ograni\u010denja prilikom prelaska granica premda se bojim da ne\u0107emo mo\u0107i sprije\u010diti ulazak tog soja u Europu. Kad vidimo koliko taj soj ima mutacija, to je jako, jako puno. Te mutacije mijenjaju izgled i strukturu S proteina toliko da ga imunosni mehanizmi koje smo stekli preboljenjem ili cijepljenjem mo\u017eda ne\u0107e mo\u0107i blokirati. Svaki put kad se pojavi novi soj, ostaje nam da vidimo kolika je njegova imunoevazivnost, \u0161to zna\u010di izbjegavanje postoje\u0107e imunosti koju je \u010dovjek stekao.<\/p>\n\n\n\n

Recimo, znamo da je originalna delta varijanta donekle imunoevazivna, odnosno na razini 20-ak posto, \u0161to zna\u010di ako imate antitijela da vas oko 80 posto tih antitijela \u0161titi, a 20 posto ne. To znamo i po cijepljenima, da se daleko vi\u0161e cijepljenih mo\u017ee inficirati delta varijantom nego \u0161to mo\u017ee prija\u0161njim varijantama. Me\u0111utim, ako ovaj novi soj bude visoko imunoevazivan, onda se vra\u0107amo na po\u010detak. A za to postoje neke naznake jer ga neki testovi nisu prepoznali. A testovi ga lo\u0161ije prepoznavaju zato \u0161to je zna\u010dajno promijenjen. \u010cujte, neke zemlje niti ne sekvencioniraju toliko, nije \u010dudno da su u Velikoj Britaniji prona\u0161li puno sojeva jer su ih jednostavno tra\u017eili \u2013 kazuje dr. Trobonja\u010da.<\/p>\n\n\n\n

U to da je virus ve\u0107 u Europi on uop\u0107e ne sumnja, \u0161to zna\u010di da \u0107e vrlo brzi sti\u0107i i do nas! Ako bi do\u0161lo do njegova sna\u017enog prodora, vjerojatno bi se s epidemijom vratili na po\u010detak.<\/p>\n\n\n\n

Me\u0111utim, dr. Trobonja\u010da smatra da je svakako va\u017eno vidjeti karakteristike novog soja virusa, dakle kakva je, osim po sposobnosti da izbjegne imunost, njegova prenosivost, odnosno sposobnost da dovede do te\u017eih oblika bolesti i smrtnosti.<\/p>\n\n\n\n

No, u svakom slu\u010daju, pored toliko uo\u010denih mutacija, \u010dak njih 32, na S proteinu, postoje\u0107a cjepiva zasigurno ne\u0107e biti u\u010dinkovita, nagla\u0161ava na\u0161 stru\u010dnjak.<\/p>\n\n\n\n

– U laboratoriju su napravili Sars-CoV-2 s 20 mutacija u S proteinu, dakle toliko su ga izmijenili da nitko od onih koji su preboljeli ili se cijepili nije imao imunost. Jedino su bili imuni oni koji su preboljeli i nakon toga se cijepili pa se za njih ka\u017ee da imaju superimunost ne samo protiv postoje\u0107ih sojeva nego i protiv svih budu\u0107ih. No ovdje imamo 32 mutacije, tako da smo sada pred neizvjesnim razdobljem \u2013 pomalo je rezigniran na\u0161 sugovornik.<\/p>\n\n\n\n

Napominje da bi se uz poznatu tehnologiju vrlo brzo moglo proizvesti cjepivo i za novi soj Sars-CoV-2 virusa, ali trebaju pro\u0107i mjeseci kako bi se ono testiralo, i sve u svemu, situacija nije ohrabruju\u0107a.<\/p>\n\n\n\n

– Ipak, ostaje nam nada da \u0107e nas i protiv ovoga soja odre\u0111ena koli\u010dina antitijela \u0161tititi, a mo\u017eda \u0107e biti manje prenosiv. Jo\u0161 je dosta rano za zaklju\u010dke. U svakom slu\u010daju, oprez je svakako dobar i zaustavljanje prometa s nekim zemljama je opravdano. A mo\u017eda taj novi soj za\u0111e u slijepu ulicu. Sve vrijeme identificiraju se nove varijante COVID-a, no one \u010desto izumru i budu istisnute zaraznijim varijantama – poja\u0161njava dr. Trobonja\u010da.<\/p>\n\n\n\n

Ina\u010de, belgijski mediji javljaju da je od B.1.1.529, tzv. afri\u010dkog soja, oboljela mlada \u017eena koja nije cijepljena i to nakon povratka iz Egipta. Znanstvenici ovaj soj smatraju supermutiranom varijantom koja je prvo zabilje\u017eena u Bocvani.<\/p>\n\n\n\n

– Najbolja mjera za\u0161tite koja nam stoji na raspolaganju je da zabranimo stranim dr\u017eavljanima da dolaze, a da na\u0161i gra\u0111ani koji dolaze iz tih zemalja idu u 14-dnevnu karantenu uz obavezno testiranje na kraju karantene – rekao je u petak glavni epidemiolog dr. Krunoslav Capak<\/strong>.<\/p>\n\n\n\n

Virusni imunolog Luka \u010ci\u010din-\u0160ain<\/strong> iz Helmholtz centra za infektolo\u0161ka istra\u017eivanja u njema\u010dkom Braunschweigu, kazao je za index.hr da za sada nema mjesta za paniku, iako ima za oprez.<\/p>\n\n\n\n

“Beta varijanta, koja je tako\u0111er izvorno primije\u0107ena u Africi, do sada je bila varijanta s najnagla\u0161enijim imunim bijegom, no bila je potisnuta varijantom delta, koju protutijela i cjepiva bolje prepoznaju, i to jer delta lak\u0161e prodire u stanice pa se i br\u017ee \u0161iri. Stoga nije sigurno ho\u0107e li se ova varijanta znatnije pro\u0161iriti”, objasnio je \u010ci\u010din-\u0160ain.<\/p>\n\n\n\n

PI\u0160E <\/strong>SILVANA UZINI\u0106\/Slobodnadalmacija.hr<\/p>\n","protected":false},"excerpt":{"rendered":"

Znanstvenici u Ju\u017enoafri\u010dkoj Republici objavili su u \u010detvrtak da su identificirali novu varijantu COVID-a 19 s vi\u0161estrukim mutacijama, koju smatraju odgovornom za velik porast broja zara\u017eenih, a ve\u0107 dan kasnije na\u0161 Nacionalni sto\u017eer civilne za\u0161tite donio je mjere ograni\u010denja na granicama za putnike iz nekoliko zemalja. Odluka o prelasku granice odnosi se na dolaske iz […]<\/p>\n","protected":false},"author":2,"featured_media":36016,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"h5ap_radio_sources":[],"footnotes":""},"categories":[1],"tags":[],"class_list":["post-93023","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bihiregija"],"yoast_head":"\nImunolog Trobonja\u010da je zabrinut: Ako novi soj virusa iz Afrike bude imao sna\u017eniji prodor, postoje\u0107a cjepiva zasigurno ne\u0107e biti u\u010dinkovita - RADIO LJUBU\u0160KI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/radioljubuski.ba\/index.php\/2021\/11\/27\/imunolog-trobonjaca-je-zabrinut-ako-novi-soj-virusa-iz-afrike-bude-imao-snazniji-prodor-postojeca-cjepiva-zasigurno-nece-biti-ucinkovita\/\" \/>\n<meta property=\"og:locale\" content=\"hr_HR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Imunolog Trobonja\u010da je zabrinut: Ako novi soj virusa iz Afrike bude imao sna\u017eniji prodor, postoje\u0107a cjepiva zasigurno ne\u0107e biti u\u010dinkovita - RADIO LJUBU\u0160KI\" \/>\n<meta property=\"og:description\" content=\"Znanstvenici u Ju\u017enoafri\u010dkoj Republici objavili su u \u010detvrtak da su identificirali novu varijantu COVID-a 19 s vi\u0161estrukim mutacijama, koju smatraju odgovornom za velik porast broja zara\u017eenih, a ve\u0107 dan kasnije na\u0161 Nacionalni sto\u017eer civilne za\u0161tite donio je mjere ograni\u010denja na granicama za putnike iz nekoliko zemalja. 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